Do You REALLY Need GLP-1 Medications Forever?
Alicia Shelly, MD FACPAugust 05, 202600:11:46

Do You REALLY Need GLP-1 Medications Forever?

"Doc, do I need to take this forever?" It's one of the most common questions I hear in my office, whether it's someone's very first visit or someone who's already lost 30, 40, even 80 pounds and is feeling great.
In this episode, I break down why your body fights so hard to regain weight after you lose it, and why that's biology, not failure. I walk through the new ATTAIN Maintain trial, a study of 376 adults who had already lost significant weight on tirzepatide or semaglutide, testing whether switching to an easier once-daily oral GLP-1 could help them keep the weight off, instead of just asking whether stopping medication causes regain.

Maintenance isn't about staying on one medication forever. It's about having an individualized, active plan, and the ATTAIN Maintain data gives us more options than ever to build one.

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